KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5DC1
All Species:
16.06
Human Site:
T435
Identified Species:
35.33
UniProt:
Q5TFE4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TFE4
NP_689942.2
455
51845
T435
F
S
S
S
N
S
K
T
A
G
Y
Y
P
N
P
Chimpanzee
Pan troglodytes
XP_518703
455
51825
T435
F
S
S
S
N
S
K
T
A
G
Y
Y
P
N
P
Rhesus Macaque
Macaca mulatta
XP_001112048
455
51828
T435
F
S
S
S
N
S
K
T
A
G
Y
Y
P
N
P
Dog
Lupus familis
XP_532271
471
53423
T451
F
S
S
S
N
S
K
T
A
G
Y
Y
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5P5
467
53076
Y445
N
N
S
K
M
A
G
Y
Y
P
L
V
H
H
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507572
133
15081
G114
K
P
G
W
Y
S
Q
G
N
A
A
H
L
Y
E
Chicken
Gallus gallus
XP_419778
454
52040
A434
S
S
N
S
S
A
T
A
G
Y
Y
P
S
P
P
Frog
Xenopus laevis
Q6GN91
499
58768
T463
L
N
Y
D
L
H
H
T
F
Y
P
K
R
T
P
Zebra Danio
Brachydanio rerio
NP_001098413
461
52643
S436
D
F
K
F
Q
R
F
S
S
E
K
P
I
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121742
508
59601
R489
K
T
K
R
A
E
Q
R
Q
R
E
G
L
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197549
242
27677
F223
K
D
A
G
K
V
T
F
L
L
T
S
S
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
83
N.A.
78.5
N.A.
N.A.
24.1
75.1
21.4
62
N.A.
N.A.
25.7
N.A.
24.4
Protein Similarity:
100
100
99.1
87
N.A.
86
N.A.
N.A.
27.2
86.3
39.4
76.7
N.A.
N.A.
42.1
N.A.
34.5
P-Site Identity:
100
100
100
93.3
N.A.
6.6
N.A.
N.A.
6.6
26.6
13.3
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
N.A.
N.A.
20
46.6
20
13.3
N.A.
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
19
0
10
37
10
10
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
10
10
0
0
0
10
% E
% Phe:
37
10
0
10
0
0
10
10
10
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
0
10
10
10
37
0
10
0
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
10
10
19
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
28
0
19
10
10
0
37
0
0
0
10
10
0
10
0
% K
% Leu:
10
0
0
0
10
0
0
0
10
10
10
0
19
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
19
10
0
37
0
0
0
10
0
0
0
0
28
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
10
10
19
37
10
55
% P
% Gln:
0
0
0
0
10
0
19
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
10
0
10
0
10
0
0
10
0
0
% R
% Ser:
10
46
46
46
10
46
0
10
10
0
0
10
19
0
0
% S
% Thr:
0
10
0
0
0
0
19
46
0
0
10
0
0
19
19
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
10
10
19
46
37
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _